ALEXANDER, RIKKI PETER,BENTLEY, JONATHAN MARK,BRACE, GARETH NEIL,BROOKINGS, DANIEL CHRISTOPHER,CHOVATIA, PRAFUL TULSHI,DEBOVES, HERVE JEAN CLAUDE,JOHNSTONE, CRAIG,JONES, ELIZABETH PEARL,KROEPLIEN, BOR
申请号：
CA2932056
公开号：
CA2932056A1
申请日:
2014.12.08
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
A series of substituted benzimidazole, imidazo[1,2-a]pyridine and pyrazolo[1,5-a]pyridine derivatives, and analogues thereof, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders； neurological and neurodegenerative disorders； pain and nociceptive disorders； cardiovascular disorders； metabolic disorders； ocular disorders； and oncological disorders.
