BROWN, JULIEN ALISTAIR,CALMIANO, MARK DANIEL,JONES, ELIZABETH PEARL,KROEPLIEN, BORIS,REUBERSON, JAMES THOMAS,SELBY, MATTHEW DUNCAN,SHAW, MICHAEL ALAN,ZHU, ZHAONING
申请号：
CA2930347
公开号：
CA2930347A1
申请日:
2014.12.08
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
A series of substituted benzimidazole, imidazo[1,2-a]pyridine and pyrazolo[1,5- a]pyridine derivatives, and analogues thereof, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders； neurological and neurodegenerative disorders； pain and nociceptive disorders； cardiovascular disorders； metabolic disorders； ocular disorders； and oncological disorders.
