BROOKINGS, DANIEL CHRISTOPHER,DE HARO GARCIA, TERESA,FORICHER, YANN,HORSLEY, HELEN TRACEY,HUTCHINGS, MARTIN CLIVE,JOHNSON, JAMES ANDREW,MACCOSS, MALCOLM,XUAN, MENGYANG,ZHU, ZHAONING
申请号：
CA3058980
公开号：
CA3058980A1
申请日:
2018.04.24
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
A compound of formula (I) as defined herein, or a pharmaceutically acceptable salt thereof, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders； neurological and neurodegenerative disorders； pain and nociceptive disorders； cardiovascular disorders； metabolic disorders； ocular disorders； and oncological disorders.
