BENTLEY, JONATHAN MARK,BROOKINGS, DANIEL CHRISTOPHER,BROWN, JULIEN ALISTAIR,CAIN, THOMAS PAUL,CHOVATIA, PRAFUL TULSHI,FOLEY, ANNE MARIE,GALLIMORE, ELLEN OLIVIA,GLEAVE, LAURA JANE,HEIFETZ, ALEXANDER,HO
申请号:
CA2877550
公开号:
CA2877550A1
申请日:
2013.07.05
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
A series of imidazo[l,2-a]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.