Jonathan Mark Bentley,Daniel Christopher Brookings,Julien Alistair Brown,Thomas Paul Cain,Praful Tulshi Chovatia,Anne Marie Foley,Ellen Olivia Gallimore,Laura Jane Gleave,Alexander Heifetz,Helen Trace
申请号:
US14414287
公开号:
US09309243B2
申请日:
2013.07.05
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A series of imidazo[1,2-a]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.