ALEXANDER HEIFETZ,ANNE MARIE FOLEY,ANTHONY JOHN RICHARDSON,BORIS KROEPLIEN,CRAIG JOHNSTONE,DANIEL CHRISTOPHER BROOKINGS,DEBORAH LEIGH,ELLEN OLIVIA GALLIMORE,FABIEN CLAUDE LECOMTE,HELEN TRACEY HORSLEY
申请号:
BR112015000675
公开号:
BR112015000675A2
申请日:
2013.07.05
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
A series of imidazo[1,2-a]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.