The present invention provides a 4-pyridylalkylthio substitiuent containing novel aromatic 5 or 6 membered heterocycle derivative of the following fomula(I) or its salt, which is useful as a medecament. The compound of the following fomula(I) or its salt is useful as a medecament for treating a disease related to neovascularization or accentuation of vascular permeability(wherein, ring A is a benzene ring or an aromatic 5 or 6 membered heterocyclic ring optionally condensed with cycloalkane ring, B is an alkylene group, R1and R2are the same or differrent, each represents a hydrogen atom, a hydroxyl group, an optionally substituted alkoxyl group etc., X and Y are the same or differrent, each represents one or several groups selected from a hydrogen atom, a halogen atom, a hydroxyl group, an optionally substituted alkoxyl group etc., p is 0, 1 or 2, q is 0 or 1) .本發明提供可作為醫藥有用之具有以4-吡啶烷硫基為取代基之新穎芳香族雜五或六員環衍生物或其鹽為課題。下述一般式[I]之化合物或其鹽可作為血管新生或血管透過性亢進參與之疾病之治療劑有用。式中，環A為苯環、或可與環烷環稠合之芳香族五或六員雜環，B為伸烷基、R1及R2可相同或相異，各為H、OH、取代或無取代烷氧基等，X及Y各可相同或相異，各為選自H、鹵素、OH、取代或無取代烷氧基等之1或複數之基、p為0、1或2，q為0或1。
