Compound of formula ** ** Formula wherein R1 and R2 represent, independently of each other, hydrogen, aminocarbonyl or (C1-C4), or R1 and R2 together with the carbon atom to which they are attached form cycloalkyl (C3-C8), R3 represents - (CH2) m- (SO2) OH or -O- (CH2) o- (SO2) OH, wherein myo independently of each other, represent an integer of 0, 1, 2 or 3, and wherein any CH2 group contained in the residues R3 represents may be substituted by one or two alkyl radicals (C1-C4), X represents CR4 or N, R4 represents hydrogen or halogen, Z represents a bond or an alkyl chain having one, two, three or four carbon atoms wherein the alkyl chain may be substituted with one, two, three or four substituents, independently selected from each other from the group It is consisting of carboxy, aminocarbonyl and (C1-C4) alkyl in which in turn may be substituted with a substituent selected from the group qu and consisting of hydroxy, carboxy and aminocarbonyl, Y represents a bond, O, NH or S, A represents (C6-C10) or 5- to 10-membered aryl and heteroaryl are substituted with a substituent of the following ** ** formula formula or wherein R1b, R2b and R3b represent, independently of each other, hydrogen, amino, hydroxy, (C1-C4) alkoxy, (C1- C4) alkyl, (C3-C6), heterocyclyl 4, 5, 6 or 7 membered heterocyclyl or 5- or 6-membered, in which amino and hydroxy may be substituted with one or two substituents independently selected from each other from the group consisting of alkylcarbonyl, (C1- C4) alkoxycarbonyl, mono- or di- (C1-C4) alkylaminocarbonyl, and (C1-C4),Compuesto de fórmula**Fórmula** en la que R1 y R2 representan, independientemente el uno del otro, hidrógeno, aminocarbonilo o alquilo (C1-C4), o R1 y R2, junto con el átomo de carbono al que están unidos, forman un cicloalquilo (C3-C8), R3 representa -(CH2)m-(SO2)OH o -O-(CH2)o-(SO2)OH, en el que m y o representan, independientemente el uno del otro, un número entero de 0, 1, 2 o 3, y en el que cualquier grupo CH2 contenido
