Henry Bernard Lowman,Luc Roland Desnoyers,Shouchun Liu
申请号：
US14528180
公开号：
US09540440B2
申请日:
2014.10.30
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention relates generally to variant activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these variant anti-EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
