HOEKMAN, JOHN D.,SATTERLY, KELSEY H.,DASHEVSKY, INNA,DAS, ADITYA R.
申请号：
CA3087698
公开号：
CA3087698A1
申请日:
2019.01.04
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Methods are provided for acute treatment of agitation, including agitation in patients with schizophrenia or bipolar disorder, comprising administering to a subject with agitation an effective dose of a dry pharmaceutical composition comprising olanzapine, wherein the dose is administered by an intranasal delivery device that provides, following intranasal administration, (a) a mean peak plasma olanzapine concentration (Cmax) of at least 30 ng/mL, with (b) a mean time to Cmax (Tmax) of olanzapine of less than 0.5 hours. Dry pharmaceutical compositions and devices suitable for intranasal delivery of olanzapine are provided.
