The invention refers to a pharmacological synthesis, which includes (1) a very strong single dispersion, including (R) - 2 - (1 - (6-amino-5-chloropyridine-4-carbohydrates) ethyl - (5-chloro-4 - (trifluoromethyl) pyridine-2-il) thiazole-5-aminomethylamine or an acceptable carbamate and a vinyl acetate (2). One or more acceptable pharmacists, treatment of cancer and preparation process. Another aspect of the invention is to provide a patient with a pharmacological composition, and the second is an intermittent dose system.La invencion se refiere a una composicion farmaceutica que comprende (1) un extruido de dispersion solida que comprende (R)-2-(1-(6-amino-5-cloropirimidina-4-carboxamido)etil)-N-(5-cloro-4-(trifluorometil)piridina-2-il)tiazol-5-carboxamida o una sal farmaceuticamente aceptable del mismo y un copolimero de acetato de vinilpirrolidinona-vinilo y (2) uno o mas excipientes farmaceuticamente aceptables, para el tratamiento de cancer y un proceso para su preparacion. la invencion tambien se refiere a la administracion de la composicion farmaceutica a un paciente segun un regimen de dosificacion intermitente
