PURPOSE: A method for manufacturing toothpaste containing complex crude drug extract is provided to maximize antibacterial and anti-inflammatory effect.CONSTITUTION: A method for manufacturing toothpaste comprises: a step A of mixing Mori Radicis Cortex, Angelicae dahuricae Radix, and Phellodendri Cortex powder in a weight ratio of 1:1:1 to prepare a sample(S101) a step B of adding 10 time weight of distilled water to the sample, heating at 80 degrees Celsius for 8 hours, and cooling to isolate active ingredients(S103) a step C of concentrating the liquid and freeze-drying to prepare complex crude drug extract(S107) and a step D of adding basic ingredients to the complex crude drug extract(S108).COPYRIGHT KIPO 2012본 발명은 치약 및 그 제조 방법에 관한 것이다.본 발명에 따르면 상백피, 백지 및 황백을 일정 중량비율로 함유함으로써 항균 및 항염 효과를 극대화한 치약에 관한 기술이 개시된다.