ROQUES, Bernard Pierre,FOURNIE-ZALUSKI, Marie-Claude,PORAS, Hervé
申请号：
ES13783036
公开号：
ES2668902T3
申请日:
2013.10.23
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
Compound of general formula (1) (1) R-NH-CH (R1) -CH2-S-S-C (R2) (R3) -COCH2-CH (R4) -COR5 wherein a) R represents: - a hydrogen； - an alkoxyalkylcarbonyl group R'C (O) OCH (R ") OC (O) - in which R 'and R" independently represent one another, an alkyl group containing from 1 to 6 carbon atoms； b) R1 represents an alkyl group, linear or branched, of 1 to 6 carbon atoms, substituted or not, by a group -OR '", -SOR'" or -SR '", with R'" representing an alkyl group from 1 to 6 carbon atoms, substituted or not, by one or more halogen atoms； c) R2 represents: - an alkyl group, linear or branched, of 1 to 6 carbon atoms, substituted or not, by: - a group -OR6, -SR6 or -SOR6, with R6 representing a hydrogen, a linear alkyl group or branched from 1 to 4 carbons, a phenyl or benzyl group； - a group -CO2R7, with R7 representing a hydrogen, a linear or branched alkyl group, comprising from 2 to 4 carbon atoms or a benzyl group； - a group -NR8R9, with R8 and R9 representing, independently of one another, a hydrogen, a linear or branched alkyl group of 1 to 4 carbon atoms, a phenyl or benzyl group, or with -NR8R9, taken together representing a saturated 5 or 6 link heterocycle comprising one or more heteroatoms selected from N or O, preferably representing a morpholine or a piperidine； or - a carboxamide group -CONR8R9, with -NR8R9 as defined above； - a phenyl group, substituted or not, by one or more halogens taken between fluorine or bromine, an alkoxy -OR6 group, with R6 having the same definition as above or by a phenyl group； - - an aromatic heterocycle of 5 or 6 links comprising 1 or 2 heteroatoms selected from oxygen, nitrogen and sulfur； - a saturated cyclic compound of 5 or 6 links or saturated heterocycle of 5 or 6 links comprising 1 or 2 heteroatoms selected from oxygen, nitrogen and sulfur； - a saturated cyclic compound of 5 or 6 links or saturated heterocyclic of 5 or 6 links comprising 1 or 2 heteroatoms selected from oxygen, nitrogen and sulfur； or - a phenyl grou
