Pearson, James Christopher,Tatton, Helen Rosemary,Gurgel, Patrick Vasconcelos
申请号：
NO20071087
公开号：
NO338345B1
申请日:
2007.02.26
申请国别(地区):
NO
年份:
2016
代理人:
摘要：
Compounds of formula (I) wherein R1 and R2 are the same or different and are each optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl or optionally substituted heteroaryl groups R3 is hydrogen or an aryl group substituent or R3 is a solid support optionally attached via a spacer Z represents an oxygen atom, a sulphur atom or NR4 Y represents an oxygen atom, a sulphur atom or NR5 in which R4 and R5, which may be the same or different, represent hydrogen, optionally substituted alkyl containing 1 to 6 carbon atoms, optionally substituted phenyl, optionally substituted benzyl or optionally substituted &bgr-phenylethyl and one of X1 and X2 represents a nitrogen atom and the other of X1 and X2 represents a nitrogen atom or CR6, in which R6 represents hydrogen or an aryl group substituent are useful for the affinity binding of a prion protein.
