The invention relates to the novel products of formula (I):in whichrepresents a single or double bond； Ra represents H, Hal, alkoxy, O-cycloalkyl, heteroaryl, phenyl, NHCOalk, NHCOcycloalk or NR1R2； X represents S, SO or SO2； A represents NH or S； W represents H, alkyl or COR with R representing cycloalkyl； alkyl optionally substituted with NR3R4, alkoxy, hydroxyl, phenyl, heteroaryl or heterocycloalkyl； alkoxy optionally substituted with NR3R4, i.e. an O-(CH2)n-NR3R4 radical, an O-phenyl radical or an O-(CH2)n-phenyl radical, with phenyl optionally substituted and n= 1 to 4； or the NR1R2 radical； R1 represents H or alk and R2 represents H, cycloalkyl or alkyl； R3 and R4 represent H, alk, cycloalkyl, heteroaryl or phenyl； R1, R2 and/or R3, R4 form, with N, a ring optionally containing O, S, N and/or NH； all heterocycloalkyls, heteroaryls, phenyls and cyclic groups being optionally substituted； these products being in any of the isomer forms and the salts, as medicaments, especially as MET inhibitors.本發明係關於式(I)之新穎產物：其中表示單鍵或雙鍵；Ra表示H、鹵素、烷氧基、O－環烷基、雜芳基、苯基、NHCO烷基、NHCO環烷基或NR1R2；X表示S、SO或SO2；A表示NH或S；W表示H、烷基或COR，其中R表示環烷基；視情況經NR3R4、烷氧基、羥基、苯基、雜芳基或雜環烷基取代之烷基；視情況經NR3R4取代之烷氧基(亦即，O－(CH2)n－NR3R4基團)、O－苯基或O－(CH2)n－苯基，其中苯基視情況經取代且n＝1至4；或NR1R2基團；R1表示H或烷基且R2表示H、環烷基或烷基；R3及R4表示H、烷基、環烷基、雜芳基或苯基；R1、R2及/或R3、R4與N一起形成視情況含有O、S、N及/或NH之環；所有雜環烷基、雜芳基、苯基及環基視情況經取代；此等產物呈任何異構體形式及鹽，作為醫藥品，尤其作為MET抑制劑。
