The present disclosure provides a compound of Formula (I)； or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are defined herein. The disclosure also relates to a method for manufacturing the compounds of the disclosure, and its therapeutic uses. The present disclosure further provides pharmaceutical composition of the compounds of the disclosure and a combination of pharmacologically active agents and a compound of the disclosure.本揭露提供了具有式(I)之化合物； 或其藥學上可接受的鹽，其中R1和R2如本文中所定義。本揭露還涉及用於製備本揭露化合物的方法及其治療用途。本揭露進一步提供了本揭露化合物的藥物組成物，以及藥理活性劑和本揭露化合物的組合。
