PURPOSE: A method for preparing Cormus officinalis fermentation extract with enhanced antioxidaiton effect is provided to increase loganin content and antioxidation effect and to effectively obtain the extract. CONSTITUTION: A method for preparing Cormus officinalis fermentation extract with enhanced antioxidation effect comprises: a step of washing Cormus officinalis and removing seeds； a step of drying and pulverizing Cormus officinalis； a step of inoculating Lactobacillus brevis(KCTC 13094) to MRS liquid medium and pre-culturing Lactobacillus brevis at 30-40 Deg.C. for 1-5 days； a step of steaming the pulverized Cormus officinalis and cooling； a step of inoculating the pre-cultured Lactobacillus brevis into steamed Cormus officinalis and fermenting； a step of adding purified water and performing hot water extraction at 100 Deg. C. for 1-3 hours； and a step of filtering and concentrating the extract by reduced pressure.본 발명은 항산화 활성을 증가시킨 산수유 발효 추출물의 제조방법에 관한 것이다. 본 발명에 따른 추출 방법은 산수유를 증기로 찌고, 이를 락토바실러스 브레비스로 발효시킨 다음 열수 추출함으로써, 로가닌 함량이 높고, 항산화 활성을 증가시킨 산수유 발효 추출물을 효율적으로 얻을 수 있다.
