Gunnar C. HANSSON,Anna ERMUND,Astrid Hilde MYRSET,Arne DESSEN,Edvar J ONSØYEN,Philip D. RYE
申请号：
US15121671
公开号：
US20160361342A1
申请日:
2015.02.27
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A method is for the treatment of a condition in a human patient arising from or associated with a defective cystic fibrosis transmembrane conductance regulator (CFTR) ion channel and/or abnormal mucus which is attached to underlying epithelium. The method includes administering an alginate oligomer, in which at least 30% of the monomer residues of the alginate oligomer are G residues, to the patient in an amount sufficient to achieve a local concentration of the alginate oligomer of 1 to 6% w/v at at least part of a mucosal surface with a defective CFTR ion channel and/or the abnormal mucus in the patient.
