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APPLICATION OF ALGINATE OLIGOMETES IN THE TREATMENT OF MUKOVISCIDOSIS AND OTHER CONDITIONS ASSOCIATED WITH THE DISTURBED FUNCTION OF CFTR ION CHANNELS
专利权人:
АльгиФарма АС (NO)
发明人:
ХАНССОН Гуннар С. (SE),ЭРМУНД Анна (SE),МЮШЕТ Астрид Хильде (NO),ДЕССЕН Арне (NO),ОНСЁЙЕН Эдвар Й (NO),РАЙ Филип Д. (NO)
申请号:
RU2016136449
公开号:
RU2016136449A
申请日:
2015.02.27
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
A method is for the treatment of a condition in a human patient arising from or associated with a defective cystic fibrosis transmembrane conductance regulator (CFTR) ion channel and/or abnormal mucus which is attached to underlying epithelium. The method includes administering an alginate oligomer, in which at least 30% of the monomer residues of the alginate oligomer are G residues, to the patient in an amount sufficient to achieve a local concentration of the alginate oligomer of 1 to 6% w/v at at least part of a mucosal surface with a defective CFTR ion channel and/or the abnormal mucus in the patient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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