ХАНССОН Гуннар С. (SE),ЭРМУНД Анна (SE),МЮШЕТ Астрид Хильде (NO),ДЕССЕН Арне (NO),ОНСЁЙЕН Эдвар Й (NO),РАЙ Филип Д. (NO)
申请号:
RU2016136449
公开号:
RU2016136449A
申请日:
2015.02.27
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
A method is for the treatment of a condition in a human patient arising from or associated with a defective cystic fibrosis transmembrane conductance regulator (CFTR) ion channel and/or abnormal mucus which is attached to underlying epithelium. The method includes administering an alginate oligomer, in which at least 30% of the monomer residues of the alginate oligomer are G residues, to the patient in an amount sufficient to achieve a local concentration of the alginate oligomer of 1 to 6% w/v at at least part of a mucosal surface with a defective CFTR ion channel and/or the abnormal mucus in the patient.