A lactic acid bacterium identified as Lactobacillus paracasei, deposited at Bioresource Collection and Research Center of Taiwan with a deposit number BCRC 910482, comprising 16S rDNA sequence presented in SEQ ID NO: 1. Lactobacillus paracasei is used in the preparation of food or medicine composition to decrease the cholesterol in blood.一種副乾酪乳酸桿菌(Lactobacillusparacasei),係寄存於中華民國食品工業發展研究所,寄存編號為BCRC 910482,該副乾酪乳酸桿菌之16S rDNA序列係包含如SEQ ID NO:1所示之序列,該副乾酪乳酸桿菌之用途係用以製備降低血液中膽固醇之食品組成物或藥物組成物。