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Data from: Mitochondrial dysfunction and infection generate immunity-fecundity tradeoffs in Drosophila
- 负责人：
- DOI：
- doi:10.5061/dryad.88mk4dh
- 摘要：
- for tradeoffs between immunity and fecundity. We found that an energetically-compromised genotype was relatively resistant to rapamycin – a drug that targets
Data from: The yeast mitochondrial pyruvate carrier is a hetero-dimer in its functional state
- 负责人：
- DOI：
- doi:10.5061/dryad.m173s71
- 摘要：
- the cytosol into the mitochondrial matrix. MPC has been implicated in many diseases and is being investigated as a drug target. A few years ago, sma
The E3-ubiquitin ligase adaptor protein Skp1 is glycosylated by an evolutionarily conserved pathway that regulates protist growth and development.pdf
- 负责人：
- 关键词：
- 60102 Bioinformatics Cell Biology Microbiology Parasitology 60307 Host-Parasite Interactions 60502 Infectious Agents 110309 Infectious Diseases Pathology 60411 Population, Ecological and Evolutionary Genetics 60109 Proteomics and Intermolecular Interactions (excl. Medical Proteomics)
- DOI：
- doi:10.6084/m9.figshare.5505661.v1
- 摘要：
- to help develop it as a drug target for control of the pathogen, as the glycosyltransferases are absent from mammalian hosts.
Data from: Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates
- 负责人：
- DOI：
- doi:10.5061/dryad.p6261d6
- 摘要：
- r molecular target, addressing a key aspect of the mechanism of action of N-BPs that may have significant clinical relevance.
Data from: Neonatal activation of the xenobiotic-sensors PXR and CAR results in acute and persistent down-regulation of PPAR?-signaling
- 负责人：
- DOI：
- doi:10.5061/dryad.0k90t
- 摘要：
- t neonatal exposure to PXR- or CAR-activators not only acutely but also persistently regulates the expression of drug-processing genes (DPGs). A single dose of the PXR
Data from: Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean childr
- 负责人：
- DOI：
- doi:10.5061/dryad.m1n03
- 摘要：
- of mass drug administration (MDA) for the prevention of recurrent P. vivax infections. Targeting hypnozoites through PQ treatment reduced the risk of having at least one qPCR
Data from: Long-term follow-up results in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents: results from
- 负责人：
- DOI：
- doi:10.5061/dryad.13d31
- 摘要：
- Objective: To assess both short and long-term prognosis in consecutive patients with coronary heart disease (CHD) treated with drug
Data from: Use of influenza antivirals in patients hospitalized in Hong Kong, 2000-2015
- 负责人：
- DOI：
- doi:10.5061/dryad.nc285
- 摘要：
- . We divided monthly admission episodes by relevant population denominators to obtain admission rates, and stratified analyses by drug type, age
Data from: The impact of hotspot-targeted interventions on malaria transmission in Rachuonyo south district in the western Kenyan highlands
- 负责人：
- DOI：
- doi:10.5061/dryad.nr8d8
- 摘要：
- . Targeting hotspots may represent an efficacious strategy for reducing malaria transmission. We determined the impact of interventions targeted
Data from: Anaesthetic interventions for prevention of awareness during surgery
- 负责人：
- 关键词：
- PTSD;anesthesia depth monitors;memory;awareness;implicit memory;explicit memory;wakefulness;BIS
- DOI：
- doi:10.5061/dryad.2vn65
- 摘要：
- , intensive care unit studies, and studies that only randomized different word presentations for memory tests (not anaesthetic interventions). Anaesthetic drug
