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Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package
- 负责人：
- 关键词：
- drug target protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases
- DOI：
- doi:10.5281/zenodo.1241027
- 摘要：
- e we present a target enabling package for the therapeutic target LIMK1. We include crystal structures of BMPR2, LIMK1, LIMK2 and the LIMK1-cofilin complex
Human LIM domain kinase 1 (LIMK1), kinase domain; A Target Enabling Package
- 负责人：
- 关键词：
- drug target protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases
- DOI：
- doi:10.5281/zenodo.1219706
- 摘要：
- e we present a target enabling package for the therapeutic target LIMK1. We include crystal structures of BMPR2, LIMK1, LIMK2 and the LIMK1-cofilin complex
LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
- 负责人：
- Eidarus Salah;;Beltrami, Alessandra;;Apirat Chaikuad;;Hanke, Thomas;;Kashima, Risa;;Canning, Peter;;Knapp, Susanne Muller;;Knaus, Petra;;Hata, Akiko
- DOI：
- doi:10.5287/bodleian:zg5naqjyk
- 摘要：
- e we present a target enabling package for the therapeutic target LIMK1. We include crystal structures of BMPR2, LIMK1, LIMK2 and the LIMK1-cofilin complex
Data from: Effect of canine oxytocin receptor gene polymorphism on the successful training of drug detection dogs
- 负责人：
- DOI：
- doi:10.5061/dryad.td13jp3
- 摘要：
- Drug detection dogs can be trained to locate various prohibited drugs with targeted odors, and they play an important role in interdiction of drug
Data from: Development and evaluation of a fluorescent antibody-drug conjugate for molecular imaging and targeted therapy of pancreatic cancer
- 负责人：
- DOI：
- doi:10.5061/dryad.6j018
- 摘要：
- more effectively than equimolar amounts of unconjugated drug. Overall, our results demonstrate that non-selective, amine-targeting chemistry
Data from: Numerical simulations of targeted delivery of magnetic drug aerosols in the human upper and central respiratory system: a validation study
- 负责人：
- DOI：
- doi:10.5061/dryad.0jt43
- 摘要：
- for further advancement of the magnetic drug targeting (MDT) technique for more efficient treatments for respiratory diseases.
Data from: Anthracycline drugs on modified surface of quercetin-loaded polymer nanoparticles: a dual drug delivery model for cancer treatment
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.5gf06
- 摘要：
- is better formulation than NF1 as loading of MTX is 85% compared to 23% loading of ADR. Such NFs are expected to overcome multi-drug resistance (MDR
Data from: Evolutionary prediction of medicinal properties in the genus Euphorbia L.
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.s2df3
- 摘要：
- e targeted approach for future phylogeny-guided drug discovery at an early screening stage, which will likely result in higher discovery rates of nove
Data from: Cell death and survival due to cytotoxic exposure modeled as a two-state Ising system
- 负责人：
- DOI：
- doi:10.5061/dryad.4qrfj6q6d
- 摘要：
- is given by an IC50 value. Chemotherapy uses both target-specific and systemic-action drugs and drug combinations to treat cancer. It is importa
Cooperia oncophora Genome Sequencing
- 负责人：
- BGI
- DOI：
- doi:10.26036/cnphis0001143
- 摘要：
- due to widespread drug resistance to all major classes of anthelmintic. This group has arguably been the subject of a substantial research effort
