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Data from: Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis
- 负责人：
- DOI：
- doi:10.5061/dryad.vh36n
- 摘要：
- introduced into clinical practice on the basis of target-based drug discovery. Fifty years later, PAS continues to be used to treat tuberculosis. PAS
Data from: Evaluation of exposure to effervescent drugs in a large health check-up population in France: a cross-sectional study
- 负责人：
- DOI：
- doi:10.5061/dryad.7h41b81
- 摘要：
- OBJECTIVES: The relationship between high dietary sodium intake and hypertension is well established. Some drugs are associated with high-sodium
-targeted therapies
- 负责人：
- DOI：
- doi:10.5061/dryad.6c44q
- 摘要：
- with the effects ascribed to the different drugs. This finding suggests that our results can highlight differences among vascular-targeted therapies, providing
Data from: Computational and experimental characterization of dVHL establish a Drosophila model of VHL syndrome
- 负责人：
- DOI：
- doi:10.5061/dryad.14pp7
- 摘要：
- s in oxygen availability as part of an E3-ligase that targets the Hypoxia-Inducible Factor for degradation. pVHL has a molten globule configuration with marg
Data from: The Alzheimer’s comorbidity phenome: mining from a large patient database and phenome-driven genetics prediction
- 负责人：
- 关键词：
- disease comorbidity;Alzheimer\u2019s disease;Systems biology;disease genetics discovery;data mining
- DOI：
- doi:10.5061/dryad.3p9b4c2
- 摘要：
- kers. This may inform a common etiology and suggest essential protein targets. US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS
Data from: Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival
- 负责人：
- DOI：
- doi:10.5061/dryad.rm7dd
- 摘要：
- mechanism underlying lung cancer drug resistance and poor clinical prognosis. Chromatin immunoprecipitation (ChIP) assays derived from non-small cell lung car
Data from: Evidence for structure and variable recombination rates among Dutch populations of the opportunistic human pathogen Aspergillus fumigatus
- 负责人：
- DOI：
- doi:10.5061/dryad.7m0797t0
- 摘要：
- and genetic differentiation contribute to the structure of Dutch A. fumigatus populations and are probably shaping the evolutionary dynamics of drug resistance in this potent
Data from: Identifying acne treatment uncertainties via a James Lind Alliance Priority Setting Partnership
- 负责人：
- DOI：
- doi:10.5061/dryad.gf1k0
- 摘要：
- uncertainties prioritised at the workshop were largely focused on management strategies, optimum use of common prescription medications and the role of non-drug
Data from: Whole genome amplification and reduced-representation genome sequencing of Schistosoma japonicum miracidia
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.8091q
- 摘要：
- to help trace the sources of new infections, and allow us to monitor drug resistance. Large-scale genotyping efforts for schistosome species hav
Data from: Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using 1H
- 负责人：
- 关键词：
- 1H-NMR
- DOI：
- doi:10.5061/dryad.64f8c
- 摘要：
- Metabolites linked to changes in choline kinase-? (CK-?) expression and drug resistance, which contribute to survival and autophagy mechanisms, ar
