Byram Bridle;Jonathan Bramson;Brian Lichty;Yonghong Wan
发明人:
Brian Lichty,Byram Bridle,Yonghong Wan,Jonathan Bramson
申请号:
US13257115
公开号:
US20120014990A1
申请日:
2010.03.16
申请国别(地区):
US
年份:
2012
代理人:
摘要:
In one aspect, a method of treating cancer in a mammal is provided. The method comprises administering to the mammal an oncolytic vector that expresses a tumour antigen to which the mammal has a pre-existing immunity. In another aspect, a method of boosting immune response in a mammal having a pre-existing immunity to an antigen is provided comprising intravenous administration to the mammal of a B-cell infecting vector that expresses the antigen.