Brian Lichty,Bryam Bridle,Yonghong Wan,Jonathan Bramson
申请号:
US15630454
公开号:
US20170348404A1
申请日:
2017.06.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
In one aspect, a method of treating cancer in a mammal is provided. The method comprises administering to the mammal an oncolytic vector that expresses a tumour antigen to which the mammal has a pre-existing immunity. In another aspect, a method of boosting immune response in a mammal having a pre-existing immunity to an antigen is provided comprising intravenous administration to the mammal of a B-cell infecting vector that expresses the antigen.