The present invention relates to a pharmaceutical composition for the prevention or treatment of bone-related diseases, which not only promotes the differentiation of preosteoblasts into osteoblasts and induces the formation of calcified nodules, but at the same time the bone marrow cells It is highly effective in preventing or treating bone-related diseases by effectively controlling bone homeostasis by suppressing the differentiation of osteoclasts to osteoclasts and suppressing the function of osteoclasts. Further, the present invention relates to a pharmaceutical composition for the prevention or treatment of menopausal diseases, in particular, in menopausal bone diseases, the volume of cancellous bone is increased, and differentiation of preosteoblasts into osteoblasts is promoted. It not only stimulates and induces the formation of calcified nodules, but at the same time, it effectively regulates bone homeostasis by suppressing the differentiation of bone marrow cells into osteoclasts and suppressing the function of osteoclasts. , It is very effective in the prevention or treatment of bone-related diseases in menopause. [Selection diagram] Figure 1本発明は、骨関連疾患の予防または治療のための薬学組成物に関し、前骨芽細胞の骨芽細胞への分化を促進して石灰化結節の生成を誘導するだけでなく、同時に、骨髄細胞の破骨細胞への分化を抑制し、破骨細胞の機能を抑制することで骨恒常性を効果的に調節して、骨関連疾患の予防または治療に非常に効果的である。また、本発明は、閉経期疾患の予防または治療のための薬学組成物に関し、特に、閉経期の骨疾患において、海綿骨の体積を増加させ、前骨芽細胞の骨芽細胞への分化を促進して石灰化結節の生成を誘導するだけでなく、同時に、骨髄細胞の破骨細胞への分化を抑制し、破骨細胞の機能を抑制することで骨恒常性を効果的に調節して、閉経期の骨関連疾患の予防または治療に非常に効果的である。【選択図】図１
