The present invention relates to an oral drug delivery composition containing oxaliplatin, which is a water-soluble anticancer drug, and a method for producing the same. More specifically, it forms a complex by an ionic bond between a bile acid derivative, which is an oral absorption enhancer, and oxaliplatin, and the complex is formed into water-in-oil-in-water (w/o/w). Incorporation into the internal aqueous phase of multiple emulsified nanoemulsions improves the oral bioavailability of oxaliplatin, which is a water-soluble anticancer drug, and makes oxaliplatin, which is currently administered only in injectable form, into a dosage form that can be orally administered. The present invention relates to an oral drug delivery composition that can be manufactured and alleviated the inconveniences and problems caused by the use of injectables, and can contribute to the improvement of patient compliance and medical cost reduction.本発明は、水溶性抗癌剤であるオキサリプラチンを含む経口用薬物送達組成物及びその製造方法に関する。さらに詳しくは、経口吸収促進剤である胆汁酸誘導体とオキサリプラチンのイオン結合による複合体を形成し、これを水中油中水型（water-in-oil-in-water；ｗ／ｏ／ｗ）の多重乳化ナノエマルションの内部水相に含ませ、水溶性抗癌剤であるオキサリプラチンの経口生体利用率を向上させ、現在注射剤形のみで投与されているオキサリプラチンを経口投与が可能な剤形に製造し、注射剤の使用による不便と問題を軽減し、患者のコンプライアンスの改善及び医療費削減に寄与できる経口用薬物送達組成物に関するものである。
