Endothelia dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.內皮功能不良(Endothelia dysfunction,ED)與許多疾病以及病症有關。非-蛋白水解活化性凝血酶受體之激動劑可用於治療ED或ED-相關的疾病以及病症之方法。