ANTI-ALFA-V INTEGRINO ANTIKŪNAS, SKIRTAS PROSTATOS VĖŽIO GYDYMUI

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专利权人:

Merck Patent GmbH

发明人:

HOFFMANN, Axel,LANNERT, Heinrich,BRISCHWEIN, Klaus,PIPP, Frederic Christian,REINDL, Jürgen,GROLL, Karin,ZUEHLSDORF, Michael,PFAFF, Otmar,RAAB, Sabine,DAU, Ulrike,DESTENAVES, Benoit

申请号：

LT12702990

公开号：

LT2672994T

申请日:

2012.02.07

申请国别(地区):

LT

年份:

2018

代理人:

摘要：

The invention is directed to the treatment of prostate cancer by means of antibodies. Above all, the invention relates to the administration of an anti-alpha-v integrin (receptor) antibody to patients suffering from prostate cancer, especially castration-resistant prostate cancer (CRPC), optionally accompanied by lymph node and bone tissue metastases (mCRPC). In particular, the invention relates to the therapy of said patients by means of the anti-angiogenic antibody DI17E6 and structural mutants thereof.

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