Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Chinese Academy of Sciences;Shanghai Institute of Materia Medica;Shanghai HaiHe Pharmaceutical Co., Ltd
发明人:
Yang, Chunhao,Meng, Linghua,Chen, Yanhong,Wang, Xiang,Tan, Cun,Li, Jiapeng,Ding, Jian,Chen, Yi
申请号：
AU2013270326
公开号：
AU2013270326B2
申请日:
2013.04.23
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The present invention relates to a pyrrolo[2,1-f][1,2,4]triazine compound, an isomer thereof or a pharmaceutically acceptable salt, ester or hydrate thereof, and a preparation method and application thereof. The pyrrolo[2,1-f][1,2,4]triazine compound has a structure expressed in general formula (I). The pyrrolo[2,1-f][1,2,4]triazine compound expressed in general formula (I) can inhibit a phosphatidylinositol-3 kinase (PI3K) signal pathway, thereby being used to prepare medicine for treating phosphatidylinositol-3 kinase related diseases such as cancer.
