SHANGHAI INSTITUTE OF MATERIA MEDICA; CHINESE ACADEMY OF SCIENCES
发明人:
YANG, CHUNHAO,MENG, LINGHUA,CHEN, YANHONG,WANG, XIANG,TAN, CUN,LI, JIAPENG,DING, JIAN,CHEN, YI
申请号：
EP13798006
公开号：
EP2857403A4
申请日:
2013.04.23
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The present invention relates to a pyrrolo[2,1- f ][1,2,4]triazine compound, an isomer thereof or a pharmaceutically acceptable salt, ester or hydrate thereof, and a preparation method and application thereof. The pyrrolo[2,1- f ][1,2,4]triazine compound has a structure expressed in general formula (I). The pyrrolo[2,1- f ][1,2,4]triazine compound expressed in general formula (I) can inhibit a phosphatidylinositol-3 kinase (PI3K) signal pathway, thereby being used to prepare medicine for treating phosphatidylinositol-3 kinase related diseases such as cancer.
