One embodiment of a composition containing 1200 mg of N-acetyl-L-cysteine and 400 mg of alpha-lipoic acid. For the purpose of eliminating many or all the symptoms of alcoholic hangover and the alcohol flushing reaction in susceptible individuals, this composition is ingested within 30 minutes prior to the initiation of drinking one or more alcoholic beverages and the same composition is ingested within 30 minutes after cessation of drinking alcoholic beverages.