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Stable compositions of povidone iodine
专利权人:
INC.;FORESIGHT BIOTHERAPEUTICS
发明人:
申请号:
ARP120103368
公开号:
AR087857A1
申请日:
2012.09.13
申请国别(地区):
AR
年份:
2014
代理人:
摘要:
Compositions containing PVP - L -, as well as methods for making such compositions, which provide reliable stability for PVP l preparations, including Preparations Containing PVP - L and one or more additional components.Claim 2: a composition suitable for topical Administration, comprising a mixture of (a) The PVP - L to a concentration of about 0.4% between Home and around 12.5% by weight (b) at least a nonsteroidal anti-inflammatory Drug (NSAID) selected from the group consisting of amfenac Bromfenac, ketotifen fumarate, diclofenac sodium, flurbiprofen, diclofenac, sadistic, ketorolac,Ketorolac tromethamine, suprofen, celecoxib, naproxen, rofecoxib, and combinations, and salts thereof, where after a period of one month after mixing the NSAID and PVP - L to form the composition, the concentration of PVP - i is at least 98% of the initial concentration of PVP - I,And after a period of six months after the mixture of NSAIDs and PVP - L to form the composition, the concentration of PVP - i is at least 96% of the concentration of PVP - I start.Claim 3: a composition suitable for topical Administration, comprising a mixture of (a) PVP - L to an initial concentration of about 0.4% and around 12.5% by weight; and (b) at least one selected from the group consisting of steroid dexamethasone, alcohol, dexamethasone, F Dexamethasone Sodium osfato fluorometholone acetate, alcohol, fluorometholone,Lotoprednol etabonate, medrysone, prednisolone acetate, Prednisolone sodium phosphate, difluprednate, rimexolone, Hydrocortisone, HYDROCORTISONE ACETATE, lodoxamide tromethamine and salts, and combinations thereof; where after a period of one month after mixing the Estero IDE and PVP - i is at least 98% of the initial concentration of PVP - LAnd after a period of six months after mixing the steroid and PVP - L to form the composition, the concentration of PVP - i is at least 96% of the initial concentration of PVP.Composiciones que contienen PVP-l-, así como también métodos para fabr
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