АКАМА Цутому (US),ЧЖАН Юн-кан (US),ДИНГ Чарльз З. (US),ПЛАТТНЕР Джейкоб Дж. (US),МЕЙПЛЗ Керк Р. (US),ФРОЙНД Ивонне (US),САНДЕРЗ Вирджиния (US),СЯ И (US),БЕЙКЕР Стефен Дж. (US),НИМАН Джеймс А. (CA),ЛУ
申请号：
RU2010140803/04
公开号：
RU2010140803A
申请日:
2009.03.05
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A compound having a structure according to the formula:! ! where Ra is a member selected from CN, C (O) NR1R2, C (O) OR3,! where R3 is a member selected from H and substituted or unsubstituted alkyl,! X is a member selected from N, CH and CRb,! Rb is a member selected from halogen and substituted or unsubstituted alkyl, C (O) R4, C (O) OR4, OR4, NR4R5,! where R1, R2, R4 and R5 are members independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl,! provided that R1 and R2 together with the atoms to which they are attached are optionally combined to form a 4-8 membered substituted or unsubstituted heterocycloalkyl ring, provided that R4 and R5 together with the atoms to which they are attached are optionally combined with the formation of a 4-8 membered substituted or unsubstituted heterocycloalkyl ring,! and salts of these compounds. ! 2. The compound according to claim 1, characterized in that R3 is a member selected from H and unsubstituted alkyl. ! 3. The compound according to claim 1, characterized in that said compound has a structure according to the formula:! . ! 4. The compound according to claim 1, characterized in that the said compound has a formula representing a member selected from:! and. ! 5. The compound according to claim 1, characterized in that the said compound has a formula representing a member selected from:! and. ! 6. The compound according to claim 1, characterized in that the said compound has a formula representing1. Соединение, имеющее структуру согласно формуле: ! ! где Ra представляет собой член, выбранный из CN, C(O)NR1R2, С(О)OR3, ! где R3 представляет собой член, выбранный из Н и замещенного или незамещенного алкила, ! X представляет собой член, выбранный из N, СН и CRb, ! Rb представляет собой член, выбранный
