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КОМПОЗИЦИИ ЦЕЛЛЮЛОЗНОГО ГЕЛЯ С УЛУЧШЕННОЙ СТАБИЛЬНОСТЬЮ ВЯЗКОСТИ
专利权人:
АЛЬКОН РИСЕРЧ; ЛТД. (US)
发明人:
ТОРРЕЛЛА Гемма (ES),АЛМЕРА Гвадалупе (ES),ГАРСЕС Хорди (ES)
申请号:
RU2014127492
公开号:
RU2014127492A
申请日:
2012.11.28
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. Multi-dose ophthalmic composition comprising: a therapeutic agent itsellyulozny polymer at a concentration sufficient for self conversion composition into a gel, said cellulosic polymer is essentially a polymer of a cellulose ester, wherein: i) said composition is substantially free of any antioxidants which would otherwise act as scavengers free radicals and inhibit oxidation reactions in the composition and ii) said composition has a pH of from 6.0 to 8,5.2. An ophthalmic composition according to Claim. 1, characterized in that said cellulosic polymer comprises gidroksietiltsellyulozu.3. An ophthalmic composition according to Claim. 1, characterized in that said cellulosic polymer essentially fully represents gidroksietiltsellyulozu.4. An ophthalmic composition according to claim. 2, characterized in that the HEC concentration in the composition is at least 2.6% but not more than 4.0% .5. An ophthalmic composition according to any one of claims. 1-4, characterized in that said therapeutic agent comprises ftorhinolon.6. An ophthalmic composition according to claim. 5, characterized in that said fluoroquinolone is moksifloksatsin.7. An ophthalmic composition according to any one of claims. 1-4, characterized in that said therapeutic agent comprises a steroidal antiinflammatory agent.8. An ophthalmic composition according to claim. 7, characterized in that said steroid antiinflammatory agent is deksametazon.9. An ophthalmic composition according to any one of claims. 1-4, characterized in that said composition is substantially free of any chemical substances distinct from said cellulosic polymer1. Многодозовая офтальмическая композиция, содержащая:терапевтический агент ицеллюлозный полимер в концентрации, достаточной для самостоятельного превращения композиции в гель, при этом указанный целлюлозный полимер по существу представляет собой полимер эфира целлюлозыгде:i) указанная композиция по существу не содержит каких-либо антиоксидантов, которые в противном случае
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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