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PHARMACEUTICAL COMPOSITIONS INCLUDING A CARBOXYVINYL POLYMER AND A POVIDONE POLYMER
专利权人:
ЛТД. (US);АЛЬКОН РИСЕРЧ
发明人:
ГАЛАН Франсиско Хавьер (ES),КАРРЕРАС Нурия (ES),ХИМЕНЕС Нурия (ES)
申请号:
RU2010151994/15
公开号:
RU2010151994A
申请日:
2009.05.12
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A pharmaceutical composition comprising:! carboxyvinyl polymer and povidone polymer; and! a destabilizing agent, which usually has a destabilizing effect on the carboxyvinyl polymer, where the povidone polymer reduces the destabilizing effect. ! 2. The pharmaceutical composition of claim 1, wherein the destabilizing agent comprises a drug and a carboxyvinyl polymer and a povidone polymer are part of a pharmaceutical carrier for the drug. ! 3. The pharmaceutical composition according to claim 2, in which the drug includes moxifloxacin. ! 4. The pharmaceutical composition according to claim 2, in which the drug comprises one or more amino-functional groups and the destabilizing effect is the lack of solubility caused by the drug, which complexes with the carboxyvinyl polymer, with the formation of the drug / carboxyvinyl polymer complex, and in which the povidone polymer helps solubilize the drug / carboxyvinyl polymer complex. ! 5. The pharmaceutical composition according to any one of claims 1 to 4, where the pharmaceutical composition or its pharmaceutical carrier is a gel. ! 6. The pharmaceutical composition according to any one of claims 1 to 4, where the pharmaceutical composition is an ophthalmic composition that includes water and has a physiologically compatible pH. ! 7. The pharmaceutical composition according to any one of claims 1 to 4, where the composition is contained in a container that releases drops of the composition in a manner suitable for topical application to the eyes. !eight. The pharmaceutical composition according to any one of claims 1 to 4, where1. Фармацевтическая композиция, содержащая: ! карбоксивиниловый полимер и повидоновый полимер; и ! дестабилизирующее средство, которое обычно обладает дестабилизирующим эффектом на карбоксивиниловый полимер, где повидоновый полимер снижает дестабилизирующий эффект. !2. Фармацевтическая композиция по п.1, где дестабилизирующее средство включает лекарственное средство и карбоксивиниловый полимер
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