Compositions for transdermal Administration of non steroidal anti-inflammatory Agents (NSAIDs) in a flexible Way Limited. The compositions comprise a Polymer Matrix that includes a NSAID and a Polymer Matrix comprising a mixture of silicone and Acrylic Polymers. It also discloses an occlusive backing material and flexible.Also described are methods for making and using the compositions and Substrates. Claim 7: the composition of any of the preceding Claims, wherein the polymer Matrix comprises approximately between 3% and 5% w / W of flurbiprofen.Claim 8: the composition of any of the preceding Claims, wherein the polymer Matrix includes between about 4 and 5% w / W of Acrylic Polymer. Claim 9: the composition of any of the preceding Claims, wherein the polymer Matrix comprises approximately 5% w / W of Acrylic Copolymer Block.Claim: the composition of any of the preceding Claims, wherein the polymer Matrix comprising up to approximately 1% w / W block copolymer of styrene isoprenoestireno.Claim 1: the composition of any of the preceding Claims, wherein the polymer Matrix comprises at least about 80% w / W of silicone Polymer.Claim 14: the composition of any of the preceding Claims, wherein the system performs the Administration of NSAIDs over a time period of at least 24 hours.Claim 18: the composition of any of Claims 16 to 17, characterized in that the support Layer includes a flexible substrate occlusive occlusive Cloth coated with a Coating.Claim: the composition of claim 18, wherein the coating comprises an occlusive polyisobutylene and / or block copolymers of styrene ISOPRENE styrene (SIS).Composiciones para la administración transdérmica de agentes antiinflamatorios no esteroideos (NSAID) en una forma flexible limitada. Las composiciones comprenden una matriz polimérica que incluye un NSAID y una matriz polimérica que comprende una mezcla de polímeros de silicona y acrílicos. Se divulga también un material de soporte oclusivo y flexible. También se de
