The invention relates to compounds of formula (I) wherein, - A 1 and A 2 , identical or different, are H, (C 1 -C 6 ) alkyl, (C 1 -C 6 ) fluoroalkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl, (C 1 -C 6 ) alkyl-OR a , (C 1 -C 6 ) alkyl-SR a , (C 1 -C 6 ) alkyl-NR a R b , OR a , SR a , NR a R b , or COR a - A 3 is H, OH or form a carbonyl with A 4 - A 4 is H, OH or form a carbonyl with A 3 - A 5 is H, OH, CR a R b OH or F - A 6 is H or F - X is CH 2 , CHF, CF 2 , CHOH, O, S, NR a or a simple bond - Y is P(O) (OR a ) (OR b ) or P(O) (OR a ) (NR a R b ) - V is O or S - A 7 is H, (C 1 -C 6 ) alkyl, (C 1 -C 6 ) fluoroalkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl or (C 1 -C 6 ) alkyl-OR a - R a and R b , identical or different, are selected from the group consisting of H, (C 1 -C 6 ) alkyl, (C 1 -C 6 ) fluoroalkyl, (C 1 -C 6 ) alkyl-OH and (C 1 -C 6 ) alkyl-O-(C 1 -C 6 ) alkyl and their addition salts thereof with acids and bases, their preparation and their use in the antibacterial prevention and therapy, used alone or in association with antibacterials, antivirulence agents or drugs reinforcing the host innate immunity.본 발명은 하기의 화학식(I)의 화합물 및 이들의 산 및 염기와의 부가염에 관한 것이며:화학식(I)- 동일하거나 다른, A1 및 A2는 H, (C1-C6)알킬((C1-C6)alkyl), (C1-C6)플루오로알킬((C1-C6)fluoroalkyl), (C2-C6)알케닐((C2-C6)alkenyl), (C2-C6)알키닐((C2-C6)alkynyl), (C1-C6)알킬-ORa((C1-C6)alkyl-ORa), (C1-C6)알킬-SRa((C1-C6)alkyl-SRa), (C1-C6)알킬-NRaRb((C1-C6)alkyl-NRaRb), ORa, SRa, NRaRb, 또는 CORa이며,- A3는 H, OH 이거나 A4와 카르보닐기(carbonyl)를 형성하고- A4는 H, OH 이거나 상기 A3와 카르보닐기(carbonyl)를 형성하며- A5는 CRaRbOH, F, OH 이거나 X가 CH인 경우에 X와 이중 결합을 형성하고- A6는 H 또는 F이며- X는 CH2, CHF, CF2, CHOH, O, S, NRa 또는 단일 결합이거나, X는 A5가 X와 이중 결합을 형성하는 경우 CH이고- Y는 P(O)(ORa)(ORb) 또는 P(O)(ORa)(NRaRb)이며- V는 O 또는 S이고- A7는 H, (C1-C6)알킬((C1-C6)alkyl), (C1-C6)플루오로알킬((C1-C6)fluoroalkyl), (C2-C6)알케닐((C2-C6)alkenyl), (C2-C6)알키닐((C2-C6)alkynyl) 또는 (C1-C6)알킬-ORa((C1-C6)alkyl-ORa)이며- A8는 OH 또는 H이고- 동일하거나 다른, Ra 및 Rb는 H, (C1-C6)알킬((C1-C6)alkyl), (C1-C6)플루오로알킬((C1-C6
