The invention relates to compounds of formula (I)wherein,- A1 and A2, identical or different, are H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, (C1-C6) alkyl-ORa, (C1-C6) alkyl-SRa, (C1-C6) alkyl-NRaRb, ORa, SRa, NRaRb, or CORa- A3 is H, OH or form a carbonyl with A4- A4 is H, OH or form a carbonyl with A3- A5 is H, OH, CRaRbOH or F- A6 is H or F- X is CH2, CHF, CF2, CHOH, O, S, NRa or a simple bond- Y is P(O) (ORa) (ORb) or P(O) (ORa) (NRaRb) - V is O or S- A7 is H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl or (C1-C6) alkyl-ORa- Ra and Rb, identical or different, are selected from the group consisting of H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C1-C6) alkyl-OH and (C1-C6) alkyl-O-(C1-C6) alkyland their addition salts thereof with acids and bases, their preparation and their use in the antibacterial prevention and therapy, used alone or in association with antibacterials, antivirulence agents or drugs reinforcing the host innate immunity.