Dale Robert Mitchell;John Frederick Atherall;Nicholas John Palmer;Christopher Richard Steele;Tamara Ladduwahetty;David John Haydon;Lloyd George Czaplewski
发明人:
David John Haydon,Lloyd George Czaplewski,Nicholas John Palmer,Dale Robert Mitchell,John Frederick Atherall,Christopher Richard Steele,Tamara Ladduwahetty
申请号：
US13154592
公开号：
US08389516B2
申请日:
2011.06.07
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Compounds of formula (I) have antibacterial activity:wherein: m is 0 or 1； Q is hydrogen or cyclopropyl； Alk is an optionally substituted, divalent C1-C6 alkylene, alkenylene or alkynylene radical which may contain an ether (—O—), thioether (—S—) or amino (—NR)— link, wherein R is hydrogen, —CN or C1-C3 alkyl； X is —C(═O)NR6—, —S(O)NR6—, —C(═O)O— or —S(═O)O— wherein R6 is hydrogen, optionally substituted C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, -Cyc, or —(C1-C3 alkyl)-Cyc wherein Cyc is optionally substituted monocyclic carbocyclic or heterocyclic having 3-7 ring atoms； Z is N or CH, or CF； R2 and R3 are as defined in the description.
