The invention relates to compounds of formulae (Ia), (Ib) or (Ic) wherein, - A1 and A2, identical or different, are H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, (C1-C6) alkyl-ORa, (C1-C6) alkyl-SRa, (C1-C6) alkyl-NRaRb, ORa, SRa, NRaRb, or CORa - A3 is H, OH or form a carbonyl with A4 - A4 is H, OH or form a carbonyl with A3 - A5 is H, CRaRbOH, F, OH or forms a double bond with X in the case where X is CH - A6 is H or F - X is CH2, CHF, CF2, CHOH, O, S, NRa or a simple bond, or X is CH in the case where A5 forms with X a double bond - Y is P(O) (ORa) (ORb) or P (O) (ORa) (NRaRb) - V is O or S - A7 is H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl or (C1-C6) alkyl-ORa - A8 is OH or H, - Ra and Rb, identical or different, are H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C1-C6) alkyl-OH or (C1-C6) alkyl-O- (C1- C6) alkyl and their addition salts thereof with acids and bases, their preparation and their use in the antibacterial prevention and therapy, used alone or in association with antibacterials, antivirulence agents or drugs reinforcing the host innate immunity.La invención se refiere a compuestos de fórmulas (la), (Ib) o (lc) donde, - A1 y A2, idénticos o diferentes, son H, alquilo de 1 a 6 átomos de carbono, fluoroalquilo de 1 a 6 átomos de carbono, alquenilo de 2 a 6 átomos de carbono, alquinilo de 2 a 6 átomos de carbono, alquilo de 1 a 6 átomos de carbono-ORa, alquilo de 1 a 6 átomos de carbono-SRa, alquilo de 1 a 6 átomos de carbono-NRaRb, ORa, SRa, NRaRb, O CORa - A3 es H, OH o forma un carbonilo con A4 - A4 es H, OH o forma un carbonilo con A3 - A5 es H, CRaRbOH, F, OH o forma un doble enlace con X en el caso donde X es CH - A6 es H o F - X es CH2, CHF, CF2, CHOH, O, S, NRa o un enlace simple, X es CH o en el caso donde A5 forma con X un enlace doble - Y es P(O)(ORa)(ORb) O P(O)(ORa)(NRaRb) - V es O o S - A7 es H, alquilo de 1 a 6 átomos de carbono, fluoroalquilo de 1 a 6 átomos de carbono, alquenilo de 2 a 6
