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NOVEL 5H-PYRROLO[2,3-D]PYRIMIDIN-6(7H)-ONE DERIVATIVE
专利权人:
TAIHO PHARMACEUTICAL CO.; LTD.
发明人:
SUGIMOTO Tetsuya,SAKAMOTO Toshihiro,YAMAMOTO Fuyuki,KOBAYAKAWA Yu,EGASHIRA Naoki,ICHIKAWA Koji,MACHIDA Takumitsu
申请号:
SG11201810360Y
公开号:
SG11201810360YA
申请日:
2017.05.19
申请国别(地区):
SG
年份:
2018
代理人:
摘要:
㻝㻜 㻌 㻝㻡 㻌 㻞㻜 㻌 㻌 Formula (I) or a salt thereof, which exhibits selected from the group consisting of Akt kinase, R 㻌 proliferation inhibiting disease s represents hetero atoms represents a hydrogen atom 㻌 one another and independently hydrogen atom independently represent different atom or the like; and 㻌 single bond one of X 㻌 The invention Formula (I) or a salt thereof, which exhibits selected from the group consisting of Akt kinase, R proliferation inhibiting s associated with the represents a - to 6 hetero atoms independently represents a hydrogen atom one another and independently hydrogen atom or the like; R independently represent different from each other and independently or the like; and single bond , and represents one of X 1 or X 2 represents N. invention of the present application Formula (I) or a salt thereof, which exhibits selected from the group consisting of Akt kinase, R proliferation inhibiting effect and is useful as a associated with the above to 6 -membered monocyclic unsaturated heterocyclic group independently represents a hydrogen atom or the like; R one another and independently or the like; R 7 independently represent a hydrogen atom from each other and independently or the like; and X3 represents N or CH when represents C when a broken line indicates a double bond, represents N. ] of the present application Formula (I) or a salt thereof, which exhibits selected from the group consisting of Akt kinase, R effect and is useful as a above -mentioned membered monocyclic unsaturated heterocyclic group independently selected from N, S and O or the like; R one another and independently represent a hydrogen atom 7 and R 8, may be the same a hydrogen atom from each other and independently represents N or CH when C when a broken line indicates a double bond, ] 㻝㻜㻤㻌 ABSTRACT of the present application Formula (I) or a salt thereof, which exhibits an inhibitory selected from the group consisting of Akt kinase, Rsk kinase, and S6K kinase effect and is
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