The invention relates to the compounds of general formula (I)in which R represents either a hydrogen or halogen atom； or a hydroxyl, (C1-C6)alkoxy, (C3-C7)cycloalkyl-O- or (C3-C7)cycloalkyl-(C1-C3)alkylene-O- group； or a heterocycloalkyl, aryl or heteroaryl group； it being possible for this group optionally to be substituted by one or more groups chosen from halogen atoms or (C1-C6)alkyl, (C3-C7)cycloalkyl, (C3-C7)cycloalkyl-(C1-C3)alkylene, (C1-C6)alkoxy, (C3-C7)cycloalkyl-O-, (C3-C7)cycloalkyl-(C1-C3)alkylene-O-, (C1-C6)fluoroalkyl, (C1-C6)fluoroalkoxy, nitro, cyano, hydroxyl, amino, (C1-C6)alkylamino or di(C1-C6)alkylamino, heterocycloalkyl, aryl, aryl-(C1-C6)alkylene, heteroaryl, heteroaryl-(C1-C6)alkylene, aryl-O- or -C(O)-(C1-C6)alkyl groups, the heterocycloalkyl group optionally being substituted by -C(O)O(CH3)3； n represents 1 or 2； m represents 1 or 2； o represents 1 or 2； in the base form or in the form of an addition salt with an acid, and also in the hydrate or solvate form.Preparation process and therapeutic application.本發明係關於通式(I)之化合物：其中R代表氫或鹵素原子；或羥基、(C1－C6)烷氧基、(C3－C7)環烷基－O－或(C3－C7)環烷基－(C1－C3)伸烷基－O－基；或雜環烷基、芳基或雜芳基；該等基團可視情況經一或多個選自下列之基取代：鹵素原子或(C1－C6)烷基、(C3－C7)環烷基、(C3－C7)環烷基－(C1－C3)伸烷基、(C1－C6)烷氧基、(C3－C7)環烷基－O－、(C3－C7)環烷基－(C1－C3)伸烷基－O－、(C1－C6)氟烷基、(C1－C6)氟烷氧基、硝基、氰基、羥基、胺基、(C1－C6)烷基胺基或二(C1－C6)烷基胺基、雜環烷基、芳基、芳基－(C1－C6)伸烷基、雜芳基、雜芳基－(C1－C6)伸烷基、芳基－O－或－C(O)－(C1－C6)烷基，該雜環烷基係視情況經－C(O)O(CH3)3取代；n代表1或2；m代表1或2；o代表1或2；其係呈鹼形式或呈與酸之加成鹽形式，以及呈水合物或溶劑化物形式。本發明亦關於該等化合物之製備方法及治療應用。
