KONDA, VEERA,URBAN, JAN,DESAI, ANURADHA,DAHLBERG, CLINTON J.,CARROLL, BRIAN J.
申请号:
CA2878594
公开号:
CA2878594A1
申请日:
2013.07.09
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present application provides novel tetrahydro-isohumulone (THIAA) derivatives and substantially enantiomerically pure compositions and pharmaceutical formulations thereof. The application further provides methods of using the disclosed compounds and compositions to activate PPARy, inhibit inflammation, and treat conditions associated with inflammation and conditions responsive to PPARy modulation such as diabetes.