Veera Konda,Jan Urban,Anuradha Desai,Clinton J. Dahlberg,Brian J. Carroll
申请号：
US15823448
公开号：
US10343977B2
申请日:
2017.11.27
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present application provides novel tetrahydro-isohumulone (THIAA) derivatives and substantially enantiomerically pure compositions and pharmaceutical formulations thereof. The application further provides methods of using the disclosed compounds and compositions to activate PPARγ, inhibit inflammation, and treat conditions associated with inflammation and conditions responsive to PPARγ modulation such as diabetes.
