Moslin, Ryan M.,Weinstein, David S.,Wrobleski, Stephen T.,Zhang, Yanlei,Tokarski, John S.,Mertzman, Michael E.,Liu, Chunjian
申请号:
NZ72071014
公开号:
NZ720710A
申请日:
2014.01.16
申请国别(地区):
NZ
年份:
2019
代理人:
摘要:
Compounds having the following formula (I): or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.