Ryan M. Moslin,Shuqun Lin,David S. Weinstein,Stephen T. Wrobleski,Yanlei Zhang,John S. Tokarski,Michael E. Mertzman
申请号:
US14441193
公开号:
US09315494B2
申请日:
2013.11.07
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Compounds having the following formula (I): or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.