Ryan M. Moslin,David S. Weinstein,Stephen T. Wrobleski,Yanlei Zhang,John S. Tokarski,Michael E. Mertzman,Chunjian Liu
申请号：
US15480787
公开号：
US09987266B2
申请日:
2017.04.06
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compounds having the following formula I:or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.
