MOSLIN, RYAN M.,WEINSTEIN, DAVID S.,WROBLESKI, STEPHEN T.,ZHANG, YANLEI,TOKARSKI, JOHN S.,MERTZMAN, MICHAEL E.,LIU, CHUNJIAN
申请号:
CA2930060
公开号:
CA2930060A1
申请日:
2014.01.16
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Compounds having the following formula (I): or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNa by acting on Tyk-2 to cause signal transduction inhibition.