The oral medicine composition or the functional food which has the mechanism of multiplex target receptor opposite action for depression remedy the butterfly plug carrot saponin (Rg1+Rb1), consists of gurichirurichin acid and jujube cAMP. As for experiment for depression remedy the medical supply of desirable until recently technology, by comparison with parokisechin, this invention proves that it possesses the considerable anti- depression effect.< Selective figure >Figure 3鬱病治療のための多重標的受容体逆作用の機序をもつ経口薬剤組成物あるいは機能性食品はチョウセンニンジンサポニン(Rg1+Rb1)、グリチルリチン酸および棗cAMPからなる。実験は鬱病治療のための望ましい従来技術の医薬品、パロキセチンと比較して、本発明は著しい抗鬱病効果を有することを実証する。【選択図】図3